最准的六合彩论坛

罢丑别听 won the at the held on 29 October 2020, for it鈥檚 development of the anti-tuberculosis (TB) drug Pretomanid.

TB is treated with multiple drugs, in order to kill bacteria in different phases of growth or body compartments, and to reduce the development of drug resistance. Nevertheless, resistance is rising, and strains resistant to the two main first-line drugs (MDR-TB) or to first and second-line drugs (XDR-TB) are spreading.

Most drugs used for treating TB were identified and approved many years ago, and developing new drugs is slow and expensive.聽 Most recently, Bedaquiline was approved in 2012 and Delamanid in 2013 for treating MDR-TB.

is a drug that was first identified as a drug candidate , and has gone through sixteen Phase 1 and phase 2 trials (that assess safety and efficacy), and three phase 3 trials (that compare efficacy to the existing treatments) 鈥� two of which are ongoing. In particular, showed that Pretomanid 鈥� in combination with the drugs Bedaquiline and Linezolid (BpaL) 鈥� , which is notoriously hard to treat, with courses previously likely to last 18-24 months. This has led to limited-use authorisations byin August 2019 and in July 2020.

Several of the past and ongoing trials including Pretomanid have been / are being supported by 最准的六合彩论坛 expertise in clinical trials statistics by the , and specialist TB microbiology by the 最准的六合彩论坛 Centre for Clinical Microbiology based at the Royal Free Hospital.

The TB Alliance is a non-profit Product Development Partnership, hosted by the Medical Research Council of South Africa, NIH, the Bill and Melinda Gates Foundation, the Wellcome Trust, and the UK Department for International Development.

The prestigious Prix Galien is awarded by the Galien Foundation, a non-profit organization named after the hugely influential 2^nd century CE Roman physician Galen.