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Publications

  • Jacobson H. D., Pan S., Fisher J. and Secrier M.

    Genome Medicine, 2;15(1):90, 2023

  • Howell R., Davies J., Clarke M.A.,ÌýAppios A., Mesquita I., Jayal Y., Ringham-Terry B., Boned Del Rio I., Fisher J.* and Bennett C.
    Science Advances, 9:15, 2023

  • Teichmann S.A., Haniffa M. & Fisher J.
    Nature Communications:Ìý13: 4068, 2022
    Ìý
  • Howell R., Clarke M.A.,ÌýReuschl A.K., Chen T., Abbott-Imboden S., Singer M., Lowe D.M., Bennett C.L., Chain B., Jolly C. and Fisher J.Ìý

    npj Digital Medicine, 5:18, 2022
    Ìý
  • Talarmain L., Clarke M.A.,ÌýShorthouseÌýD., Fisher J. and Hall B.A.

    Nature Communications:Ìý13: 5829, 2022
    Ìý
  • Clarke M.A.Ìý& Fisher J.Ìý

    Nature Reviews Cancer 20: 343-354,Ìý2020

  • Hall B. & Fisher J.

    Current Protocols in Bioinformatics, 69, e95,Ìý2020

  • Schneider P., Walters P, Plowright T., Sieroka N., Listgarten J., Goodnow R., Fisher J., Jansen J., Duca J., Rush T., Zentgraf M., Hill J., Krutoholow E., Kohler M., Blaney J., Funatsu K. & Schneider G.

    Nature Reviews Drug Discovery 19: 353-364,Ìý2020
    Ìý
  • Clarke M.A.Ìý& Fisher J.

    Nature Biomedical Engineering, 3:847-849, 2019
    Ìý
  • Kreuzaler P., Clarke M.A.,ÌýBrown E., Wilson C.H., Piterman N., Littlewood T., Evan G.I. & Fisher J.

    PNAS, 116(44): 22399-22408, 2019
    Ìý
  • Koksal A., Beck K., McKenna A., Srivastava S., Bodik R., Wolf-Yadlin A., Fraenkel E., Fisher J., & Gitter A.

    Cell Reports, 24:3607–3618, 2018
    Ìý
  • Yu M.K, Ma J., Fisher J., Kreisberg J.F., Raphael B.J. & Ideker T.

    Cell 173: 1562-1565, 2018
    Ìý
  • Paterson Y., Shorthouse D., Pleijzier M., Piterman N., Bendtsen C., Hall B.Ìý & Fisher J.

    Integrative Biology 10:370-382, 2018
    Ìý
  • Woodhouse S., Piterman N., Wintersteiger C., Gottgens B., & Fisher J.

    BMC Sys Biol 12:59, 2018
    Ìý
  • Fisher J. & Woodhouse S.

    Current Opinion in Systems Biology, 4:64–70, 2017
    Ìý
  • Silverbush D., Grosskurth S., Wang D., Powell F., Gottgens B., Dry J.R. & Fisher J.

    Cancer Research, 77(4), February 2017
    Ìý
  • Lim C.Y., Wang H., Woodhouse S., Piterman N., Wernisch L., Fisher J., & Gottgens B.

    BMC Bioinformatics 17:355, September 2016
    Ìý
  • Woodhouse S.J., Moignard V., Gottgens B., & Fisher J.

    Immunology and Cell Biology, pp 1-10, November 2015
    Ìý
  • Hall B., Piterman N., Hajnal A., & Fisher J.

    Biophysical Journal, 109:428-438, 2015
    Ìý
  • Moignard V., Woodhouse S., Haghverdi L., Lilly J, Tanaka Y, Wilkinson A.C, Buettner F., Nishikawa S.I., Piterman N., Kouskoff V., Theis F.J., Fisher J., & Göttgens B.

    Nature Biotechnology, 33, 269–276, 2015
    Ìý
  • Chuang R., Benque D., Cook B., Hall B.A., Ishtiaq S., Piterman N., Taylor A., Vardi M., Koschmieder S., Gottgens B. & Fisher J.

    Nature Scientific Reports, 5:8190, 2015
    Ìý
  • Taylor A., Fisher J., Cook B., Ishtiaq S., & Piterman N.
    Modelling biology – working through (in-)stabilities and frictions
    Computational Culture, 2014
    Ìý
  • Fisher J., Piterman N., & Rastislav Bodik.
    Towards Synthesizing Executable Models in Biology
    Frontiers in Bioengineering and Biotechnology, section Bioinformatics and Computational Biology. December 2014.
    Ìý
  • Wilkinson A., Kawata V.K.S., Schütte J., Gao X., Antoniou S., Baumann C., Woodhouse S., Hannah R., Tanaka Y., Swiers G., Moignard V., Fisher J., Hidetoshi S., Tijssen M.R., de Bruijn M.F.T.R., Liu P., & Göttgens B.
    Single cell analyses of regulatory network perturbations using enhancer targeting TAL Effectors suggest novel roles for PU.1 during haematopoietic specification
    Development, 141: 1-13, 2014
    Ìý
  • Hall B., Jackson E., Hajnal A., & Fisher J.
    Logic Programming to Predict Cell Fate Patterns and Retrodict Genotypes during Organogenesis
    Royal Society Interface, 11: 0140245, 2014
    Ìý
  • Moignard V., Woodhouse S., Fisher J., & Gottgens B.
    Transcriptional Hierarchies Regulating Early Blood Cell Development
    Blood Cells, Molecules, and Diseases, 2013
    Ìý
  • Ilsley G., Fisher J., Apweiler R., DePace A. & Luscombe N.
    Cellular resolution models of cis-regulatory input function in the entire Drosophila embryo
    eLife, 2:e0052, 2013
    Ìý
  • Snoek B., van der Velde K., Arends D., Li Y., Beyer A., Elvin M., Fisher J., Hajnal A., Hengartner M., Poulin G., Rodriguez M., Schmid T., Schrimpf S., Xue F., Jansen R., Kammenga J., & Swertz M.
    WormQTL – Public archive and analysis web portal for natural variation data in Caenorhabditis
    Nucleic Acid Research, 40(21): 1-6, 2012
    Ìý
  • Nusser-Stein S., Beyer A., Adamczyk M., Rimann I., Piterman N., Hajnal A., & Fisher J.
    Cell-Cycle Regulation of Notch Signalling During C. elegans Vulval Development
    Molecular Systems Biology, Featured Article 8:618, 2012
    Ìý
  • Feiglin A., Hacohen A., Sarusi A., Fisher J., Unger R., & Ofran Y.
    Static network structure can be used to model the phenotypic effects of perturbations in regulatory networks
    Bioinformatics, 28(21): 2811–2818, 2012
    Ìý
  • Fisher J., Harel D., & Henzinger T.A.
    Biology as Reactivity
    Communications of ACM 54 (10): 72-82, 2011
    Ìý
  • Bonzanni N., Zhang N., Oliver S., & Fisher J.
    The role of proteosome-mediated proteolysis in modulating the activity of potentially harmful transcription factor activity in Saccharomyces cerevisiae
    Bioinformatics, 27: i283–i287, 2011
    Ìý
  • Fisher J. & Nir Piterman.
    The Executable Pathway to Biological Networks
    Briefings in Functional Genomics & Proteomics, 9(1): 79-92, 2010
    Ìý
  • Beyer A., Thomson P., Scott J., & Fisher J.
    Computational Modelling of Metabolic Disturbance in Fat Tissue during Type-2 Diabetes and Obesity
    Transactions in Computational Systems Biology, LNBI 5945, pp. 146–162, 2010
    Ìý
  • Wang D., Cardelli L., Piterman N., & Fisher J.
    Computational modelling of the EGFR network elucidates control mechanisms regulating signal dynamics
    BMC Systems Biology 3:118, 2009
    Ìý
  • Kugler H., Kam N., Marelly R., Appleby L., Fisher J., Pnueli A., Harel D., Hubbard E.J.A., & Stern M.J.
    A scenario-based approach to modeling development (II): A Prototype Model of C. elegans Vulval Cell Fate Specification
    Developmental Biology, 323:1–5, 2008
    Ìý
  • Sadot A., Fisher J., Barak D., Admanit Y., Stern M., Hubbard J., & Harel D.
    Towards verified biological models
    Transactions on Computational Biology and Bioinformatics, 5(2):1-12, 2008
    Ìý
  • Fisher J. & Henzinger T.A.
    Executable Cell Biology
    Nature Biotechnology, 25(11):1239-1249, 2007
    * See also Correspondence in Nature Biotechnology 26(7): 738-739, 2008
    Ìý
  • Fisher J., Piterman N., Hajnal A., & Henzinger T.A.
    Predictive modeling of signaling crosstalk during C. elegans vulval development
    PLoS Computational Biology, 3(5):e92, 2007
    Ìý
  • Schaub M., Henzinger T.A., & Fisher J.
    Qualitative networks: A symbolic approach to analyze biological signaling networks
    BMC Systems Biology 1:4, 2007
    Ìý
  • Fisher J., Piterman N., Hubbard J., Stern M., & Harel D.
    Computational insights into C. elegans vulval development
    PNAS. 102 (6): 1951-1956, 2005
    * See also Nature Reviews Genetics 6 (4): 255, 2005.
    Ìý
  • Schwartz M., Shaked I., Fisher J., Mizrahi T., & Schori H.
    Protective autoimmunity against the enemy within: Fighting glutamate toxicity
    Trends in Neuroscience 26(6):297-302, 2003
    Ìý
  • Wolf S., Fisher J., Bechman I., Steiner B., Kwidzinski E., & Nitsch R.
    Neuroprotection by T-cells depends on their subtype and activation state
    Journal of Neuroimmunology 133:72-80, 2002
    Ìý
  • Fisher J., Mizrahi T., Schori H., Yoles E., Levkovich-Verbin H., Haggiag S., Ravel M., & Schwartz M.
    Increased post-traumatic survival of neurons in IL-6 knockout mice on a background of EAE susceptibility
    Journal of Neuroimmunology 119:1-9, 2001
    Ìý
  • Fisher J., Levkovitch-Verbin H., Schori H., Yoles E., Butovsky O., Kaye J.F., Ben-Nun A., & Schwartz M.
    Vaccination for neuroprotection in the mouse optic nerve: Implications for optic neuropathies
    The Journal of Neuroscience 21(1): 136-142, 2001

Book Chapters & Books

  • Clarke M., Woodhouse S., Piterman N., Hall B. and Fisher J.
    Using State Space Exploration to Determine How Gene Regulatory Networks Constrain Mutation Order in Cancer Evolution
    Automated Reasoning for Systems Biology and Medicine, Springer, 2019
    Ìý
  • Fisher J. & Piterman N.
    Model Checking for Biology
    System Theoretic and Computational Perspectives in Systems and Synthetic Biology, Springer-Verlag, 2014
    Ìý
  • Beyer A., Eberhard R., Piterman N., Hengartner M.O., Hajnal A., and Fisher J.
    A Dynamic Physical Model of Cell Migration, Differentiation and Apoptosis in Caenorhabditis elegans
    Advances in Systems Biology, Springer, 2012
    Ìý
  • Fisher J. & Harel D.
    On Statecharts for Biology
    Symbolic Systems Biology: Theory and Methods, Jones and Bartlett Publishers, 2010
    Ìý
  • Fisher J. (Ed.).
    Formal Methods in Systems Biology
    Springer, 2008

Computer Science Papers

  • Ahmed Z., Benque D., Berezin S., Dahl C., Fisher J., Hall B., Ishtiaq S., Nanavati J., Piterman N., Riechert M., Skoblov N.
    Bringing LTL Model Checking to Biologists.
    Verification, Model Checking and Abstract Interpretation (VMCAI), LNCS 10145, pp. 1-13, Springer, 2017
    Ìý
  • Woodhouse S., Piterman N., Köksal A. and Fisher J.
    Synthesizing Executable Gene Regulatory Networks from Single-Cell Gene Expression Data
    CAV LNCS 9206, pp. 544-560, Springer-Verlag, 2015
    Ìý
  • Cook B., Fisher J., Hall B., Ishtiaq S., Juniwal G., and Piterman N.
    Efficient Verification of Cyclic Instability in Biological Models
    CAV LNCS 8559, pp. 358-372, Springer, 2014
    Ìý
  • Claessen K., Fisher J., Ishtiaq S., Piterman N., and Wang Q.
    Model-Checking Signal Transduction Networks through Decreasing Reachability Sets
    CAV LNCS 8044, pp. 85-100, Springer-Verlag, 2013
    Ìý
  • Taylor A., Benque D., Bourton S., Cockerton C., Cook B., Fisher J., Ishtiaq S., Piterman N.
    At the Intersection of Biology and Computation
    CHI pp. 493-502 ACM, 2013
    Ìý
  • Koksal A., Pu Y., Srivastava S., Bodik R., Fisher J., and Piterman N.
    Synthesis of Biological Models from Mutation Experiments
    POPL pp. 469-482 ACM, 2013Ìý
    Ìý
  • Benque D., Bourton S., Cockerton C., Cook B., Fisher J., Ishtiaq S., Piterman N., Taylor A., and Vardi M.
    Bio Model Analyzer: Visual Tool for Modeling and Analyzing Biological Networks
    CAV 2012, LNCS 7358, pp. 686–692, Springer Verlag, 2012
    Ìý
  • Beyer A., Eberhard R., Piterman N., Hengartner M., Hajnal A., and Fisher J.
    Predictive Modelling of Stem Cell Differentiation and Apoptosis in C. elegans
    9th International Conference on Information Processing in Cells and Tissues (IPCAT), LNCS 7223, pp. 99–104, Springer Verlag, 2012
    Ìý
  • Fisher J., Henzinger T.A., Nickovic D., Piterman N., Singh A.V., and Vardi M.Y.
    Dynamic reactive Modules
    Concur 2011, LNCS 6901, pp. 404–418, 2011
    Ìý
  • Fisher J., Piterman N., & Vardi M.
    Tower of Abstractions in Biology: The Only Way Is Up
    Formal Methods 2011, Invited Paper. LNCS 6664, pp. 3–11, 2011
    Ìý
  • Cook B., Fisher J., Krepska E., & Piterman N.
    Proving stabilization for biological systems
    Proceedings of 12th International Conference on Verification, Model Checking and Abstract Interpretation Conference VMCAI ’11 R. Jhala and D. Schmidt (Eds.), LNCS vol. 6538, pages 134-149, 2011
    Ìý
  • Church L., Apagyi K., & Fisher J.
    Supporting Life Scientists via End User Programming
    Proceedings of the 2008 Microsoft eScience Workshop
    Ìý
  • Church L., Apagyi K., & Fisher J.
    Languages for biological models: Importance, implications and challenges
    Proceedings of the Psychology of Programming Interest Group, 2008
    Ìý
  • Fisher J., Henzinger T.A., Mateescu M., & Piterman N.
    Bounded Asynchrony for Modeling Cell-Cell Interactions
    Proceedings of FMSB ’08 Cambridge, UK. Lecture Notes in Bioinformatics, 5054: pages 17-32, Springer-Verlag, 2008
    Ìý
  • Schaub M., Bezdek A., Henzinger T.A., Radtke F., & Fisher J.
    Qualitative Crosstalk Analysis of Wnt and Notch Signaling in Mammalian Skin
    RECOMB Systems Biology, ’07 San Diego, CA. Lecture Notes in Bioinformatics
    Ìý
  • Fisher J. & Henzinger T.A.
    Executable Biology
    Proceedings of the 2006 Winter Simulation Conference - Track on Modeling and Simulation in Computational Biology pp. 1675-1682, 2006
    Ìý
  • Fisher J., Harel D., Hubbard J., Piterman N., Stern M., & Swerdllin N.
    Combining state-based and scenario-based approaches in modeling biological systems
    Proceedings of CMSB ‘04 Paris, France. Lecture Notes in Bioinformatics 3083: 236-241, Springer-Verlag, 2004